VEGF and diabetic microvascular complications
نویسندگان
چکیده
منابع مشابه
PKC inhibition and diabetic microvascular complications.
In patients with diabetes, the hyperglycaemia is known to promote high levels of diacylglycerol which activates protein kinase C (PKC) in the vascular tissues and leads to production of vascular endothelial growth factor (VEGF) in the retina. PKC activation is likely to play a key role in diabetic microvascular complications, particularly changes in vascular permeability and ischaemia in the re...
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1 School of Public Health, Aarhus University, Denmark 2 Division of Human Nutrition, Wageningen University, The Netherlands 3 University of Sheffield, UK 4 Department of Epidemiology and Public Health, University College London, London, UK 5 Albert Einstein College of Medicine, Rose F. Kennedy Center, USA 6 International Centre for Circulatory Health, National Heart & Lung Institute, Imperial C...
متن کاملJointly sponsored by The Dulaney Foundation and Diabetic Microvascular Complications
STATEMENT OF NEED The combination of abdominal obesity, hypertension, dyslipidemia, abnormal glucose metabolism and coagulopathy is known as the metabolic syndrome. This combination leads to atherosclerosis and subsequent coronary artery disease and its associated conditions. Insulin resistance plays a major role in the development of type 2 diabetes and in the metabolic abnormalities seen with...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 1997
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/12.7.1538a